Structure of PDB 5lzb Chain z Binding Site BS06

Receptor Information
>5lzb Chain z (length=614) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAYWPQPDG
RVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQ
LTGNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFITAATE
GRGMDALREHLLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGE
VKVGDSLWLTGVNKPMRVRALHAQNQPTETANAGQRIALNIAGDAEKEQI
NRGDWLLADVPPEPFTRVIVELQTHTPLTQWQPLHIHHAASHVTGRVSLL
EDNLAELVFDTPLWLADNDRLVLRDISARNTLAGARVVMLNPPRRGKRKP
EYLQWLASLARAQSDADALSVHLERGAVNLADFAWARQLNGEGMRELLQQ
PGYIQAGYSLLNAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMAL
PMEDEALVLLLIEKMRESGDIHSHHGWLHLPDHKAGFSEEQQAIWQKAEP
LFGDEPWWVRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRI
VEFANMIRDLDQECGSTCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRG
NDHLLRDALLFPEK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5lzb Chain z Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5lzb The pathway to GTPase activation of elongation factor SelB on the ribosome.
Resolution5.3 Å
Binding residue
(original residue number in PDB)		T14 T37
Binding residue
(residue number reindexed from 1)		T14 T37
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) K13 T14 T37 H61
Catalytic site (residue number reindexed from 1) K13 T14 T37 H61
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
GO:0032561 guanyl ribonucleotide binding
GO:0035368 selenocysteine insertion sequence binding
GO:0043168 anion binding
Biological Process
GO:0001514 selenocysteine incorporation
GO:0006412 translation
GO:0016259 selenocysteine metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5lzb, PDBe:5lzb, PDBj:5lzb
PDBsum5lzb
PubMed27842381
UniProtP14081|SELB_ECOLI Selenocysteine-specific elongation factor (Gene Name=selB)

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