Structure of PDB 6zym Chain u Binding Site BS06

Receptor Information
>6zym Chain u (length=157) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIY
KGKKFNARKETVQNEVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTME
HGATRNFQLNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEA
MLRQHRL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6zym Chain u Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6zym Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		C43 C46 C80 C83
Binding residue
(residue number reindexed from 1)		C42 C45 C79 C82
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000398 mRNA splicing, via spliceosome

View graph for
Biological Process
External links
PDB RCSB:6zym, PDBe:6zym, PDBj:6zym
PDBsum6zym
PubMed33007253
UniProtQ9BW85|YJU2_HUMAN Splicing factor YJU2 (Gene Name=YJU2)

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