Structure of PDB 2om1 Chain R Binding Site BS06

Receptor Information
>2om1 Chain R (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
Ligand IDRCO
InChIInChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H
InChIKeyGHMLBKRAJCXXBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1cc(cc(c1)O)O
ACDLabs 10.04
CACTVS 3.341		Oc1cccc(O)c1
FormulaC6 H6 O2
NameRESORCINOL;
1,3-BENZENEDIOL;
1,3-DIHYDROXYBENZENE
ChEMBLCHEMBL24147
DrugBankDB11085
ZINCZINC000000002028
PDB chain2om1 Chain Q Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2om1 Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH.
Resolution1.97 Å
Binding residue
(original residue number in PDB)		H10 L11
Binding residue
(residue number reindexed from 1)		H10 L11
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:2om1, PDBe:2om1, PDBj:2om1
PDBsum2om1
PubMed18093308
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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