Structure of PDB 1wv7 Chain L Binding Site BS06

Receptor Information
>1wv7 Chain L (length=142) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQC
ASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQ
YCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1wv7 Chain L Residue 1005 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1wv7 Structure-based design of P3 moieties in the peptide mimetic factor VIIa inhibitor
Resolution2.7 Å
Binding residue
(original residue number in PDB)		A1 N2 E6 E7 E16 E26
Binding residue
(residue number reindexed from 1)		A1 N2 E6 E7 E16 E26
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1wv7, PDBe:1wv7, PDBj:1wv7
PDBsum1wv7
PubMed15629154
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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