Structure of PDB 8edg Chain G Binding Site BS06

Receptor Information
>8edg Chain G (length=550) Species: 7370 (Musca domestica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDNLEVKAKINQGLYKITPRHKGTSFIWNVLADIQKEDDTLVEGWVFCRK
CEKVLKYTTRQTSNLCRHKCCASLKQSRELKTVSADCKKEAIEKCAQWVV
RDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTS
DAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNE
LRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANV
VKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANL
QHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHIN
KSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDV
ADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEF
CLSKMEDPVCPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLAL
SLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8edg Chain G Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8edg Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Resolution4.64 Å
Binding residue
(original residue number in PDB)		C51 C54 H71 C73
Binding residue
(residue number reindexed from 1)		C48 C51 H68 C70
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0046872 metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8edg, PDBe:8edg, PDBj:8edg
PDBsum8edg
PubMed37491363
UniProtQ25438

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