Structure of PDB 6b40 Chain E Binding Site BS06

Receptor Information
>6b40 Chain E (length=553) Species: 7741 (Branchiostoma belcheri) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SCMTPEECLGMRLDMLMTKNQYSKEYNILKERGFSTLCPPKQLDAIEKTL
MPGTARYSLEPDSVTMDFHEYVPDFPCPNTKGVRFPYAHAVAKTLEELED
EIVNGLKKLGRDPNDPTLVIHTICKDGADGMGDVSVHKEKSDHLLPDKAL
RFSFCVLRCSVMHKDTEVTIYEDPNPNSVRSNRPVLECIGDENDDGTVAV
CVGPIECQRLLMKDKIMRVHMSDGTQRAHYLTFFNSMVDEKWDRAHGGLA
GAGSKYLCTLCEAVRDEALEKAGSYKITRTLKKIEVTASKMKYESQEKDT
FGVKGYPLLTTEPWERGIDATHTDINMGNYFKSLIVREMAQVHSWAKTAN
VKKQIVDAESKLDKHLKESLGLNPTLMMAGNYARELFKAEHADKLVALVD
KPDRKSALVEVLAKFRQLRKVYRANWPLNDMSDEVRQYKAKAVEMANDLK
THFPYAPCTNYLHKVIEHVQELIEHPSGVGSVGALSSEGNEAGNKLFRQL
RLGHARKGNTYNGLRDVLCTHWLYTSKTLRDKAAAAAAAAAAAAAAAAAA
AAA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6b40 Chain E Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6b40 Transposon molecular domestication and the evolution of the RAG recombinase.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		D701 G702
Binding residue
(residue number reindexed from 1)		D129 G130
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6b40, PDBe:6b40, PDBj:6b40
PDBsum6b40
PubMed30971819
UniProtA0A185KID9

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