Structure of PDB 6xny Chain C Binding Site BS06

Receptor Information
>6xny Chain C (length=548) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKV
LLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRY
DSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKH
GSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSVLCCKPLCLML
ADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDE
KLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEV
WRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQ
LEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMMMNGNFARKLMT
QETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQY
SFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASE
GNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6xny Chain C Residue 1101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6xny Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D600 G601 E962
Binding residue
(residue number reindexed from 1)		D141 G142 E503
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6xny, PDBe:6xny, PDBj:6xny
PDBsum6xny
PubMed32945578
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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