Structure of PDB 5ze0 Chain C Binding Site BS06

Receptor Information
>5ze0 Chain C (length=623) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTL
FLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKM
YRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGI
IDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLD
DYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHG
SQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKS
SELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTR
LEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPF
IETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLD
KHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMD
LYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITN
YFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEM
EDVLKHHWLYTSKYLQKFMNAHN
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5ze0 Chain C Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5ze0 Cracking the DNA Code for V(D)J Recombination
Resolution2.75 Å
Binding residue
(original residue number in PDB)		D600 E962
Binding residue
(residue number reindexed from 1)		D216 E578
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:5ze0, PDBe:5ze0, PDBj:5ze0
PDBsum5ze0
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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