Structure of PDB 7qee Chain B Binding Site BS06

Receptor Information
>7qee Chain B (length=739) Species: 32630 (synthetic construct) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQM
SLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVV
DVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARN
HIDPAAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGE
EWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQG
EELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRF
EEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSI
VNGLLRDQLGFTGYVNSNTGIINDRAWGLEGNTVPERVAAAINGGTDTLS
GFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVAT
ATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTE
ETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSL
GLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTD
NRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVI
LHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPF
ALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYEDD
Ligand information
Ligand IDBDP
InChIInChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2-,3+,4-,6+/m0/s1
InChIKeyAEMOLEFTQBMNLQ-QIUUJYRFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0[C@@H]1([C@@H]([C@H](O[C@H]([C@@H]1O)O)C(=O)O)O)O
OpenEye OEToolkits 1.7.0C1(C(C(OC(C1O)O)C(=O)O)O)O
CACTVS 3.370O[CH]1O[CH]([CH](O)[CH](O)[CH]1O)C(O)=O
ACDLabs 12.01O=C(O)C1OC(O)C(O)C(O)C1O
CACTVS 3.370O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O
FormulaC6 H10 O7
Namebeta-D-glucopyranuronic acid;
beta-D-glucuronic acid;
D-glucuronic acid;
glucuronic acid
ChEMBLCHEMBL1159524
DrugBankDB03156
ZINCZINC000004097543
PDB chain7qee Chain B Residue 817 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qee Functional metagenomic screening identifies an unexpected beta-glucuronidase.
Resolution2.374 Å
Binding residue
(original residue number in PDB)		R136 N186 Y258 R272 K318 H319 Y369 T416
Binding residue
(residue number reindexed from 1)		R97 N147 Y211 R225 K271 H272 Y322 T369
Annotation score4
Gene Ontology
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UnboundLocalError		Python 3.6.8: /usr/bin/python3
Fri Nov 15 22:56:39 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()
   1435     title=pdb2title(pdbid)
   1436     if bs.startswith("BS"):
=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)
   1438     else:
   1439         if lig3:
pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '7qee', asym_id = 'B', bs = 'BS06', title = 'Functional metagenomic screening identifies an unexpected beta-glucuronidase.'
 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='7qee', asym_id='B', bs='BS06', title='Functional metagenomic screening identifies an unexpected beta-glucuronidase.')
   1295         display_ec(ec,csaOrig,csaRenu)
   1296     if go:
=> 1297         display_go(go,uniprot,pdbid,asym_id)
   1298     return pubmed,uniprot
   1299 
global display_go = <function display_go>, go = '0004553,0005975', uniprot = '', pdbid = '7qee', asym_id = 'B'
 /var/www/html/BioLiP/pdb.cgi in display_go(go='0004553,0005975', uniprot='', pdbid='7qee', asym_id='B')
    480         '''.replace("$namespace_link",namespace_link
    481           ).replace("$namespace",namespace
=>  482           ).replace("$uniprot",u
    483         ))
    484         for l,(term,name) in enumerate(go2aspect[Aspect]):
u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>