Structure of PDB 4okd Chain B Binding Site BS06

Receptor Information
>4okd Chain B (length=792) Species: 3055 (Chlamydomonas reinhardtii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FCEPSGQPASTAYGPALTGRPAPLGASIDADTGAINFSVFSSSAESVSLV
LFTEADLNAGRATFEIPLDPYVNRTGDVWHIMLPDLRDDLLYGYRVEGVH
QEEDKDYPGMRHDKRRVVLDPYAVAVLNRRRWGQMGPNLPYGEEGVLGVM
PTWPQAAAALPAASAFDWEGDTPLNLPMESLVIYEAHVRGFTAHASSGVA
APGTYAGMVERLDYLKSLGVNAIELLPVFEFNELEYYSQIPGSDQYRFNF
WGYSTVNYFSPMGRFSAAVGQGAPARASCDEFKQLVKECHRRGIEVILDV
VFNHTAEGNERGPTISFRGLDNRVYYMLAPGGEYYNYSGCGNTLNCNQPV
VRQFILDCLKHWVTEYHVDGFRFDLASILTRAHSAWHPQQYDQETGQRVA
MSSGGAIVTAEGIMTDGAGVPTGYPLADPPLVESISEDPVLRNTKMIAEA
WDCDGLNQVGAFPHYGGRWSEWNGKFRDVVRNFIKGTDGPWAGDFASAIC
GSPNIYANNTPHETDWWANNGGRQWKGGRGPHASINFVAAHDGFTLADMV
AYNNKHNEANDGEQHNNSWNCGEEGPTTKWEVNRLRQRQMRNLTGALLLS
CGVPMINMGDEYGHSKNGNNNTYCHDSELNYLRWDQLAEDPHGFNRFVRL
LIHFRRATPALQRTTFVNDKDIQWHGELPNTPDWTDTSRLVAFTLHDGKG
GGLYVAFNTSHLPKLLQLPKWGGRVWQPLVDTSKVAPYDFLAVDGVLSAE
DVAAARRQMAMWTADHTYPVLPWSCIVLQSAPEDPAATSMIK
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain4okd Chain G Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4okd Crystal Structure of the Chlamydomonas Starch Debranching Enzyme Isoamylase ISA1 Reveals Insights into the Mechanism of Branch Trimming and Complex Assembly.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		G571 A574 S575 W767
Binding residue
(residue number reindexed from 1)		G493 A496 S497 W684
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) F77 R205 E308 F309 M340 D452 E527 D620
Catalytic site (residue number reindexed from 1) F1 R129 E230 F231 M262 D374 E449 D542
Enzyme Commision number 3.2.1.68: isoamylase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0019156 isoamylase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0009507 chloroplast

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4okd, PDBe:4okd, PDBj:4okd
PDBsum4okd
PubMed24993830
UniProtQ7X8Q2

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