Structure of PDB 4dwz Chain B Binding Site BS06

Receptor Information
>4dwz Chain B (length=265) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LINTDIGNRGVLKVYLDYRRKNFNFLHNSTKMFLDNLERVLIVTGFPIPP
MMVAETDGPPGALAIYRAVEMLGGKAEILTYSEVEKALEPFGVSLARTPE
PEDYSLIISVETPGRAADGRYYSMSALEIKRDPLDGIFLKARALGIPTIG
VGDGGNEIGMGKIRELVVGHVPHGEKIASVVETDELIVSAVSNWGAYGLV
AQASIEVGRNLLEGWDERRVIEAISSAGLIDGVSKTLAPSVDGIRLMVHE
GIVELLKAVVDEAIL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4dwz Chain B Residue 307 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4dwz Experimental phasing using zinc anomalous scattering
Resolution2.7 Å
Binding residue
(original residue number in PDB)		E254 E258
Binding residue
(residue number reindexed from 1)		E250 E254
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0047820 D-glutamate cyclase activity
Biological Process
GO:0006536 glutamate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4dwz, PDBe:4dwz, PDBj:4dwz
PDBsum4dwz
PubMed22948927
UniProtB6YTD8

[Back to BioLiP]