Structure of PDB 2ebs Chain B Binding Site BS06

Receptor Information
>2ebs Chain B (length=771) Species: 203496 (Geotrichum sp. M128) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HYEFKNVAIGGGGYITGIVAHPKTKDLLYARTDIGGAYRWDAGTSKWIPL
NDFIEAQDMNIMGTESIALDPNNPDRLYLAQGRYVGDEWAAFYVSEDRGQ
SFTIYESPFPMGANDMGRNNGERLAVNPFNSNEVWMGTRTEGIWKSSDRA
KTWTNVTSIPDAFTNGIGYTSVIFDPERNGTIYASATAPQGMYVTHDGGV
SWEPVAGQPSSWLNRTTGAFPDKKPASIAPQPMKVALTPNFLYVTYADYP
GPWGVTFGEVWRQNRTSGAWDDITPRVGNSSPAPYNNQTFPAGGFCGLSV
DATNPNRLVVITLDRDPGPALDSIYLSTDAGATWKDVTQLSSPSNLEGNW
GHPTNAARYKDGTPVPWLDFNNGPQWGGYGAPHGTPGLTKFGWWMSAVLI
DPFNPEHLMYGTGATIWATDTLSRVEKDWAPSWYLQIDGIEENAILSLRS
PKSGAALLSGIGNISGMKHDDLTKPQKMFGAPQFSNLDSIDAAGNFPNVV
VRAGSSGHEYDSACARGAYATDGGDAWTIFPTCPPGMNASHYQGSTIAVD
ASGSQIVWSTKLDEQASGPWYSHDYGKTWSVPAGDLKAQTANVLSDKVQD
GTFYATDGGKFFVSTDGGKSYAAKGAGLVTGTSLMPAVNPWVAGDVWVPV
PEGGLFHSTDFGASFTRVGTANATLVSVGAPKSSAPSAVFIWGTDKPGSD
IGLYRSDDNGSTWTRVNDQEHNYSGPTMIEADPKVYGRVYLGTNGRGIVY
ADLTKSTAKCANGQKGTHCYV
Ligand information
Ligand IDXYS
InChIInChI=1S/C5H10O5/c6-2-1-10-5(9)4(8)3(2)7/h2-9H,1H2/t2-,3+,4-,5+/m1/s1
InChIKeySRBFZHDQGSBBOR-LECHCGJUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C1C(C(C(C(O1)O)O)O)O
CACTVS 3.341O[CH]1CO[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.5.0C1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O
CACTVS 3.341O[C@@H]1CO[C@H](O)[C@H](O)[C@H]1O
ACDLabs 10.04OC1C(O)COC(O)C1O
FormulaC5 H10 O5
Namealpha-D-xylopyranose;
alpha-D-xylose;
D-xylose;
xylose;
XYLOPYRANOSE
ChEMBL
DrugBankDB03389
ZINCZINC000001529214
PDB chain2ebs Chain D Residue 7 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2ebs The Structural Basis for the Exo-mode of Action in GH74 Oligoxyloglucan Reducing End-specific Cellobiohydrolase.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		W255 G380
Binding residue
(residue number reindexed from 1)		W253 G378
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.150: oligoxyloglucan reducing-end-specific cellobiohydrolase.
Gene Ontology
Molecular Function
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0033945 oligoxyloglucan reducing-end-specific cellobiohydrolase activity
Biological Process
GO:0010411 xyloglucan metabolic process
GO:0030245 cellulose catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2ebs, PDBe:2ebs, PDBj:2ebs
PDBsum2ebs
PubMed17498741
UniProtQ8J0D2|CBHRE_GEOS1 Oligoxyloglucan reducing end-specific cellobiohydrolase

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