Structure of PDB 7zcp Chain A Binding Site BS06

Receptor Information

>7zcp Chain A (length=341) Species: 566679 (Bradyrhizobium sp. ORS 375)

DDLKLPRQRVDLVAPPFVHVHEQATKQGPKIMEFKLVVQEKKMVIDEKGT
TFQAMTFNGSMPGPLMVVHEGDYVEVTLVNPATNTMPHNIDFHSATGALG
GGALTLINPGEQVVLRWKATRTGVFVYHCAPGGPMIPWHVVSGMNGAVMV
LPRDGLNDGHGHSLRYDRIYYIGEQDLYVPRDEKGNFKSYDSPGEAYSDT
EEVMRKLTPTHVVFNGKAGALTGKNALNANVGENVLIVHSQANRDSRPHL
IGGHGDYVWETGKFSNAPETGLETWFIRGGSAGAALYKFLQPGIYAYVTH
NLIEAANLGATAHFKVEGKWNDDLMTQVKAPADIPTGSTNE

Ligand information

• Ligand ID: NO2
• InChI: InChI=1S/HNO2/c2-1-3/h(H,2,3)/p-1
• InChIKey: IOVCWXUNBOPUCH-UHFFFAOYSA-M
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341: [O-]N=O
  OpenEye OEToolkits 1.5.0: N(=O)[O-]
• Formula: N O2
• Name: NITRITE ION
• DrugBank: DB12529
• PDB chain: 7zcp Chain A Residue 420

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7zcp Single crystal spectroscopy and multiple structures from one crystal (MSOX) define catalysis in copper nitrite reductases.
• Resolution: 1.29 Å
• Binding residue (original residue number in PDB): S61 M62 N216
• Binding residue (residue number reindexed from 1): S60 M61 N215
• Annotation score: 5

Enzymatic activity

• Enzyme Commision number: 1.7.2.1: nitrite reductase (NO-forming).

Gene Ontology

Molecular Function

• GO:0005507 copper ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0050421 nitrite reductase (NO-forming) activity

Biological Process

• GO:0019333 denitrification pathway
• GO:0042128 nitrate assimilation

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:7zcp, PDBe:7zcp, PDBj:7zcp
• PDBsum: 7zcp
• PubMed: 35862453
• UniProt: H0SLX7