Structure of PDB 7y85 Chain A Binding Site BS06

Receptor Information
>7y85 Chain A (length=1232) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRIT
LRNEHAKKLLLASLGFVDKLCGALCRIEVIDHNDELRKQAEVIVEAFKQN
DKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKVQGT
ALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGFRILGDTEYYS
SDLFIPVTPPEGIETKEWIIVGRLKAATPFYFGVQQPSDSIPGKENEHTS
FNILLDKENRYRIPRSALRGALRRDLRTAFGSGCNVSLGGQILCNCKVCI
EMRRITLKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPEGLTF
PFVLRYRGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFALKDI
KIFEWDLNQKINEYIKERGMRGKEKELLEMGESSLPDGLIPYKFFEEREC
LFPYKENLKPQWSEVQYTIEVGSPLLTADTISALTEPGNRDAIAYKKRVY
NDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCDMCII
FGNEHESSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTGGALDKAKFDT
YPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLGSKGG
VGYGWVAGISIDDNVINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKV
YREKDIITHEEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPG
HKNYKFFNINGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTLSASKT
LGGKLDKALHPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLI
TRGNNPERSLTLGVLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQ
LEIRETVQPERNVTTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGKN
IAHKLGKGKPYGFGSVKIKIDSLHTFKIKRVPQSDIREYINKGYQKLIEW
SGLPQWHVIPHIDKLYKLLWVPFLNDSKLEPDVRYPVLNEESKGYIEGSD
YTYKKLGDKDNLPYKTRVKGLTTPWSPWNPFQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7y85 Chain A Residue 1804 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y85 Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase
Resolution2.73 Å
Binding residue
(original residue number in PDB)		G134 D137 A139
Binding residue
(residue number reindexed from 1)		G129 D132 A134
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7y85, PDBe:7y85, PDBj:7y85
PDBsum7y85
PubMed36477448
UniProtA0A0B0EGF3

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