Structure of PDB 7y84 Chain A Binding Site BS06

Receptor Information
>7y84 Chain A (length=1242) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRIT
LRNEHAKKLLLASLGFVDKLCGALCRIEVIDHNDELRKQAEVIVEAFKQN
DKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKVQGT
ALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGRFRILGDTEYYS
SDLFIPVTPPEGIETKEWIIVGRLKAATPFYFGVQQPSDSIPGKEKLVIN
EHTSFNILLDKENRYRIPRSALRGALRRDLRTAFGSGCNVSLGGQILCNC
KVCIEMRRITLKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPE
GLTFPFVLRYRGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFA
LKDIKIFEWDLNQKINEYIKERGMRGKEKELLEMGESSLPDGLIPYKFFE
ERECLFPYKENLKPQWSEVQYTIEVGSPLLTADTISALTEPGNRDAIAYK
KRVYNDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCD
MCIIFGNEHESSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTGGALDKA
KFDTYPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLG
SKGGVGYGWVAGISIDDNVPDDFKEMIINNDYVHPGHQSPKQDHKNKNIY
YPHYFLDSGSKVYREKDIITHEEFTEELLSGKINCKLETLTPLIIPDTSD
ENGLKLQGNKPGHKNYKFFNINGELMIPGSELRGMLRTHFEALTKSCFAI
FGEDSTLSASKTLGGKLDKALHPCTGLSDGLCPGCHLFGTTDYKGRVKFG
FAKYENGPEWLITRGNNPERSLTLGVLESPRPAFSIPDDESEIPGRKFYL
HHNGWRIIRQKQLEIRETVQPERNVTTEVMDKGNVFSFDVRFENLREWEL
GLLLQSLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHTFKIKRVPQSDIRE
YINKGYQKLIEWSGLPQWHVIPHIDKLYKLLWVPFLSKLEPDVRYPVLNE
ESKGYIEGSDYTYKKLGDKDNLPYKTRVKGLTTPWSPWNPFQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7y84 Chain A Residue 1805 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7y84 Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase
Resolution2.61 Å
Binding residue
(original residue number in PDB)		G134 D137 A139
Binding residue
(residue number reindexed from 1)		G129 D132 A134
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7y84, PDBe:7y84, PDBj:7y84
PDBsum7y84
PubMed36477448
UniProtA0A0B0EGF3

[Back to BioLiP]