Structure of PDB 7y81 Chain A Binding Site BS06

Receptor Information
>7y81 Chain A (length=1223) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRIT
LRNEHAKKLLLASLGFVDKLCGALCRIEVIDHNDELRKQAEVIVEAFKQN
DKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKVQGT
ALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETTEYYSSDLFIPVT
PPEGIETKEWIIVGRLKAATPFYFGVQQPSDSIPGKEVINEHTSFNILLD
KENRYRIPRSALRGALRRDLRTAFGSGCNVSLGGQILCNCKVCIEMRRIT
LKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPEGLTFPFVLRY
RGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFALKDIKIFEWD
LNQKINEYIKERGMRGKEKELLEMGESSLPDGLIPYKFFEERECLFPYKE
NLKPQWSEVQYTIEVGSPLLTADTISALTEPGNRDAIAYKKRVYNDGNNA
IEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCDMCIIFGNEHE
SSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTGGALDKAKFDTYPLAGS
PKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLGSKGGVGYGWV
AGISIDDNVINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDI
ITHEEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKF
FNINGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTLSASKTLGGKLD
KALHPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLITRGNNP
ERSLTLGVLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQLEIRET
VQPERNVTTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGKNIAHKLG
KGKPYGFGSVKIKIDSLHTFKIKRVPQSDIREYINKGYQKLIEWSGLPQW
HVIPHIDKLYKLLWVPFLNDSKLEPDVRYPVLNEESKGYIEGSDYTYKKL
GDKDNLPYKTRVKGLTTPWSPWN
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7y81 Chain A Residue 1804 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7y81 Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase
Resolution2.54 Å
Binding residue
(original residue number in PDB)		G134 D137 A139
Binding residue
(residue number reindexed from 1)		G129 D132 A134
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7y81, PDBe:7y81, PDBj:7y81
PDBsum7y81
PubMed36477448
UniProtA0A0B0EGF3

[Back to BioLiP]