Structure of PDB 7n4p Chain A Binding Site BS06

Receptor Information
>7n4p Chain A (length=207) Species: 28377 (Anolis carolinensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNRLPYFINYFFDTYLLINEDTPVGSSVTQLLARDLDNDPLVFGVVGEEA
SRFFAVESMTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIKGSVNIQVGD
VNDNAPRFHNQPYSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSFQPS
SNFFTIDSGRGIVSVIRALDYEVTQAYQLQVNATDQDKTKPLSTLANLAI
TITDVQD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7n4p Chain A Residue 306 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7n4p Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation.
Resolution2.097 Å
Binding residue
(original residue number in PDB)		E118 D169 E171
Binding residue
(residue number reindexed from 1)		E119 D170 E172
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7n4p, PDBe:7n4p, PDBj:7n4p
PDBsum7n4p
PubMed36911992
UniProtR4GAX0

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