Structure of PDB 7kd5 Chain A Binding Site BS06

Receptor Information

>7kd5 Chain A (length=428) Species: 152219,1327989

IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVA
ATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNG
KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNL
QEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKN
KHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFK
GQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGA
VALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAA
SGRQTVDAALAAAQTNAAAKSSAASPAALSGYKMTLLALIKESIPNQAKR
QKFEMQVGGIRNEQDFKNLRREIIRSAA

Ligand information

• Ligand ID: PRO
• InChI: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
• InChIKey: ONIBWKKTOPOVIA-BYPYZUCNSA-N
• SMILES:
  OpenEye OEToolkits 1.5.0: C1C[C@H](NC1)C(=O)O
  CACTVS 3.341: OC(=O)[C@@H]1CCCN1
  CACTVS 3.341: OC(=O)[CH]1CCCN1
  OpenEye OEToolkits 1.5.0: C1CC(NC1)C(=O)O
  ACDLabs 10.04: O=C(O)C1NCCC1
• Formula: C5 H9 N O2
• Name: PROLINE
• ChEMBL: CHEMBL54922
• DrugBank: DB00172
• ZINC: ZINC000000895360
• PDB chain: 7kd5 Chain A Residue 1408

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7kd5 Structural Analysis of the Menangle Virus P Protein Reveals a Soft Boundary between Ordered and Disordered Regions.
• Resolution: 1.551 Å
• Binding residue (original residue number in PDB): Y242 G243
• Binding residue (residue number reindexed from 1): Y241 G242
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0015144 carbohydrate transmembrane transporter activity

Biological Process

• GO:0008643 carbohydrate transport
• GO:0055085 transmembrane transport

External links

• PDB: RCSB:7kd5, PDBe:7kd5, PDBj:7kd5
• PDBsum: 7kd5
• PubMed: 34578318
• UniProt: A0A4P1LXE0;
  Q91MK1