Structure of PDB 7eap Chain A Binding Site BS06

Receptor Information
>7eap Chain A (length=755) Species: 510516 (Aspergillus oryzae RIB40) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKPRYKDPSVPVEERVTDLLGRMTLEEKMSQLIQGDITNWMNETTGEFNL
TGLEWSTKMRGGMFYVGYPVPWDYIADNVKKAQDYILQNTTLGIPAIVQT
ESLHGFLIGNATIYNSPIGFACSFNPELIEKMARLIGQEASALGVNHVMG
PVVDLARELRFGRVEETYGEDPFLAGEIGYHYTKGIQSHNISANVKHFVG
FSQPEQGLNTAPVHGGERYLRTTWLPSFKRAIMDAGAWSIMSAYHSYDGI
PAVADYHTLTEILREEWGYKYWVTSDAGASDRVCTAFKLCRADPIDKEAV
TLAILPAGNDVEMGGGSYNFETIIDLVNAGKLDIEIVNTAVSRVLRAKFE
MGLFENPYNAAPASEWNKLIHTQEAVDLARELDRESIVLLENHDNALPLK
KSGSIAVIGPMAHGFMNYGDYVVYESQYRGVTPLDGIKAAVGDKATINYA
QGCERWSNDQSGFAEAVEAAKKSDVAVVVVGTWSRDQKELWAGLNATTGA
HVDVNSLSLVGAQAPLIKAIIDTGVPTVVVLSSGKPITEPWLSNNTAALV
QQFYPSEQGGNALADVLFGDYNPSGKLSVSFPHSVGDLPIYYDYLNSARE
IGDAGYIYSNGTLEFGHQYALGNPKAWYPFGYGKSYSSFEYGAVKLDKTN
VTEADTVTVSVDVKNTDATREGTEVVQVYVVDEVASVVVPNRLLKGFKKV
VIPAGQTKTVEIPLKVQDLGLWNVRMKYVVEPGAFGVLVGSSSEDIRGNA
TFYVQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7eap Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7eap Structural basis for the catalytic mechanism of the glycoside hydrolase family 3 isoprimeverose-producing oligoxyloglucan hydrolase from Aspergillus oryzae.
Resolution1.42 Å
Binding residue
(original residue number in PDB)		D706 V708
Binding residue
(residue number reindexed from 1)		D682 V684
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.21: beta-glucosidase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0008422 beta-glucosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0046872 metal ion binding
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0009251 glucan catabolic process
Cellular Component
GO:0005575 cellular_component

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7eap, PDBe:7eap, PDBj:7eap
PDBsum7eap
PubMed35717558
UniProtQ2U8V9

[Back to BioLiP]