Structure of PDB 6wmi Chain A Binding Site BS06

Receptor Information
>6wmi Chain A (length=146) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRL
KVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGC
GRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6wmi Chain A Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wmi ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
Resolution2.75 Å
Binding residue
(original residue number in PDB)
C311 C316 H329 H333
Binding residue
(residue number reindexed from 1)
C95 C100 H113 H117
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6wmi, PDBe:6wmi, PDBj:6wmi
PDBsum6wmi
PubMed33301730
UniProtQ86VK4|ZN410_HUMAN Zinc finger protein 410 (Gene Name=ZNF410)

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