Structure of PDB 6j7o Chain A Binding Site BS06

Receptor Information
>6j7o Chain A (length=290) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPYSSPPTNLRSLRDRLTQVAERQGVVFGRLQRHVAMIVVAQFAATLTDD
TGAPLLLVKGGSSLELRRGIPDSRTSKDFDTVARRDIELIHEQLADAGET
GWEGFTAIFTAPEEIDVPGMPVKPRRFTAKLSYRGRAFATVPIQVSSVEA
GNADQFDTLTSDALGLVGVPAAVAVPCMTIPWQIAQKLHAVTAVLEEPKV
NDRAHDLVDLQLLEGLLLDADLMPTRSACIAIFEARAQHPWPPRVATLPH
WPLIYAGALEGLDHLELARTVDAAAQAVQRFVARIDRATK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6j7o Chain A Residue 310 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6j7o Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D51 P56 R86
Binding residue
(residue number reindexed from 1)		D49 P54 R84
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6j7o, PDBe:6j7o, PDBj:6j7o
PDBsum6j7o
PubMed32382148
UniProtP96356

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