Structure of PDB 6go7 Chain A Binding Site BS06
Receptor Information
>6go7 Chain A (length=338) Species:
10090
(Mus musculus) [
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KISQYACQRRTTLNNYNQLFTDALDILAENDELRENEGSCLAFMRASSVL
KSLPFPITSMKDTEGIPCLGDKVKSIIEGIIEDGESSEAKAVLNDERYKS
FKLFTSVFGVGLKTAEKWFRMGFRTLSKIQSDKSLRFTQMQKAGFLYYED
LVSCVNRPEAEAVSMLVKEAVVTFLPDALVTMTGGFRRGKMTGHDVDFLI
TSPEATEDEEQQLLHKVTDFWKQQGLLLYHQYHRSFERSFCILKLDHGRV
HSGKGWKAIRVDLVMCPYDRRAFALLGWTGSRQFERDLRRYATHERKMML
DNHALYDRTKRVFLEAESEEEIFAHLGLDYIEPWERNA
Ligand information
Ligand ID
MG
InChI
InChI=1S/Mg/q+2
InChIKey
JLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341
[Mg++]
Formula
Mg
Name
MAGNESIUM ION
ChEMBL
DrugBank
DB01378
ZINC
PDB chain
6go7 Chain A Residue 603 [
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Receptor-Ligand Complex Structure
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PDB
6go7
Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction.
Resolution
2.55 Å
Binding residue
(original residue number in PDB)
D343 D345
Binding residue
(residue number reindexed from 1)
D195 D197
Annotation score
1
Enzymatic activity
Enzyme Commision number
2.7.7.31
: DNA nucleotidylexotransferase.
2.7.7.7
: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003887
DNA-directed DNA polymerase activity
GO:0016779
nucleotidyltransferase activity
GO:0034061
DNA polymerase activity
Biological Process
GO:0006281
DNA repair
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Molecular Function
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Biological Process
External links
PDB
RCSB:6go7
,
PDBe:6go7
,
PDBj:6go7
PDBsum
6go7
PubMed
31138645
UniProt
P09838
|TDT_MOUSE DNA nucleotidylexotransferase (Gene Name=Dntt);
Q9JIW4
|DPOLM_MOUSE DNA-directed DNA/RNA polymerase mu (Gene Name=Polm)
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