Structure of PDB 6eet Chain A Binding Site BS06

Receptor Information
>6eet Chain A (length=443) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDD
VQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSS
ATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVY
SIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANL
RVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKAT
DRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFK
FQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIEDLTE
ILDRYVQEQIPGAKVVVESIGARRHGDAYSLEDYSKCDLTVYAIDPQTNR
AIDRNELFKFLDGKLLDINKDFQPYYGEGGRILEIRTPEAVTS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6eet Chain A Residue 1411 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6eet Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
Resolution3.23 Å
Binding residue
(original residue number in PDB)		E1026 D1075 E1077 D1118
Binding residue
(residue number reindexed from 1)		E128 D177 E179 D220
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6eet, PDBe:6eet, PDBj:6eet
PDBsum6eet
PubMed32963095
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

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