Structure of PDB 4zpl Chain A Binding Site BS06

Receptor Information
>4zpl Chain A (length=316) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATIRYSVAEEMESGSFVANVAKDLGLEVGKLAERGARLVAEGNRLHFRLH
RKTGDLFVKEKLDREALCGKSDPCVLHFEIILAEPLQSFRVEVRVFDIND
NAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSANTYF
HLHTRFRSHGPKYAELVLDNPLDREAQPEVNLTITAVDGGSPPKSGTANI
RVVVLDVNDHVPQFSRLVYRAQVPENSDNGSLVVVVTATDLDEGTNKQIT
YSLAENPEAVLRTFLVDPQTGEVRLRGPLDFEMIETYDIDIQATDGGGLS
AHSKVLVEVVDVNDHH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4zpl Chain A Residue 418 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4zpl Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		N208 H210 D240 D242 D295
Binding residue
(residue number reindexed from 1)		N208 H210 D240 D242 D295
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4zpl, PDBe:4zpl, PDBj:4zpl
PDBsum4zpl
PubMed26478182
UniProtQ91Y08

[Back to BioLiP]