Structure of PDB 4zbc Chain A Binding Site BS06
Receptor Information
>4zbc Chain A (length=387) Species:
1929
(Streptomyces rubiginosus) [
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NYQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVESVRRLAELGAHGV
TFHDDDLIPFGSSDSEREEHVKRFRQALDDTGMKVPMATTNLFTHPVFKD
GGFTANDRDVRRYALRKTIRNIDLAVELGAETYVAWGGREGAESGGAKDV
RDALDRMKEAFDLLGEYVTSQGYDIRFAIEPKPNEPRGDILLPTVGHALA
FIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQNG
IKYDQDLRFGAGDLRAAFWLVDLLESAGYSGPRHFDFKPPRTEDFDGVWA
SAAGCMRNYLILKERAAAFRADPEVQEALRASRLDELARPTAADGLQALL
DDRSAFEEFDVDAAAARGMAFERLDQLAMDHLLGARG
Ligand information
Ligand ID
FRU
InChI
InChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1
InChIKey
RFSUNEUAIZKAJO-ARQDHWQXSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OC1C(O)C(OC1(O)CO)CO
OpenEye OEToolkits 1.5.0
C([C@@H]1[C@H]([C@@H]([C@](O1)(CO)O)O)O)O
CACTVS 3.341
OC[CH]1O[C](O)(CO)[CH](O)[CH]1O
OpenEye OEToolkits 1.5.0
C(C1C(C(C(O1)(CO)O)O)O)O
CACTVS 3.341
OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O
Formula
C6 H12 O6
Name
beta-D-fructofuranose;
beta-D-fructose;
D-fructose;
fructose
ChEMBL
CHEMBL604608
DrugBank
ZINC
ZINC000001529270
PDB chain
4zbc Chain A Residue 409 [
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Receptor-Ligand Complex Structure
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PDB
4zbc
A generic protocol for protein crystal dehydration using the HC1b humidity controller.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
W20 D24 Y254 Q256 K289
Binding residue
(residue number reindexed from 1)
W19 D23 Y253 Q255 K288
Annotation score
2
Enzymatic activity
Catalytic site (original residue number in PDB)
H54 D57 M88 E181 K183 E217 H220 D245 D255 D257 D287
Catalytic site (residue number reindexed from 1)
H53 D56 M87 E180 K182 E216 H219 D244 D254 D256 D286
Enzyme Commision number
5.3.1.5
: xylose isomerase.
Gene Ontology
Molecular Function
GO:0000287
magnesium ion binding
GO:0009045
xylose isomerase activity
GO:0016853
isomerase activity
GO:0042802
identical protein binding
GO:0046872
metal ion binding
Biological Process
GO:0005975
carbohydrate metabolic process
GO:0042732
D-xylose metabolic process
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:4zbc
,
PDBe:4zbc
,
PDBj:4zbc
PDBsum
4zbc
PubMed
27139626
UniProt
P24300
|XYLA_STRRU Xylose isomerase (Gene Name=xylA)
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