Structure of PDB 4kyw Chain A Binding Site BS06

Receptor Information
>4kyw Chain A (length=254) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFENNRP
VADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLT
YTKNFEVNNFLVLPKQFVTPKSIIQRKPLAPTANRAGWIGCNIDLSQVPS
KGRIFLVQDGQVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIE
GSEFTLEDMYRFESDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGK
YRKL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4kyw Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4kyw Structural basis of the methylation specificity of R.DpnI.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		D53 E64 L65
Binding residue
(residue number reindexed from 1)		D53 E64 L65
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:4kyw, PDBe:4kyw, PDBj:4kyw
PDBsum4kyw
PubMed24966351
UniProtP0A459|T2D1_STRPN Type II methyl-directed restriction enzyme DpnI (Gene Name=dpnC)

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