Structure of PDB 3ugx Chain A Binding Site BS06

Receptor Information
>3ugx Chain A (length=369) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVY
VSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVGASGATTRLQESLI
KKLGANTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEIKAFATHSTD
VEEDKIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVS
LSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNVVLYSSDYYIKT
VAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLAS
STIIKEGIDKTVMGILVSYQIKVKLTVSGLLGELTSSEVATEVPFRLMHP
QPEDDENFVFEEFARQNLK
Ligand information
Ligand IDPTD
InChIInChI=1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
InChIKeySXRSQZLOMIGNAQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC=O)CC=O
ACDLabs 10.04
CACTVS 3.341		O=CCCCC=O
FormulaC5 H8 O2
NamePENTANEDIAL
ChEMBLCHEMBL1235482
DrugBankDB03266
ZINCZINC000001729593
PDB chain3ugx Chain A Residue 410 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ugx Crystal Structure of p44, a Constitutively Active Splice Variant of Visual Arrestin.
Resolution2.649 Å
Binding residue
(original residue number in PDB)		P127 C128 V130 Q178 S308 S309 T310 I311
Binding residue
(residue number reindexed from 1)		P119 C120 V122 Q170 S300 S301 T302 I303
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001664 G protein-coupled receptor binding
Biological Process
GO:0002031 G protein-coupled receptor internalization
GO:0007165 signal transduction
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005829 cytosol
GO:0016020 membrane
GO:0042995 cell projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ugx, PDBe:3ugx, PDBj:3ugx
PDBsum3ugx
PubMed22306737
UniProtP08168|ARRS_BOVIN S-arrestin (Gene Name=SAG)

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