Structure of PDB 2qt6 Chain A Binding Site BS06

Receptor Information
>2qt6 Chain A (length=498) Species: 5365 (Lentinus tigrinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVGPVADLTVTNANIVPDGFERAAIVVNNVFPAPLITGNMGDNFQLNLVN
QMTNHTMLKTTSIHWHGFFQKGTNWADGPAFINQCPIASGNSFLYDFQVP
GQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPHANLYDVDDESTVITLAD
WYHVAAKLGPRFPKGADSTLINGLGRSTSTPTADLAVISVTKGKRYRFRL
VSLSCDPNYTFSIDSHQLTVIEADGVSTQPVTVDSIQIFAAQRYSFVLNA
NQDVDNYWIRANPNFGTTGFADGVNSAILRYDDADPVEPVTNQTGTTLLL
ETDLHPLTSMPVPGNPTQGGADLNLNMAFNFDGTNFFINGESFTPPTVPV
LLQIISGANTAQDLLPSGSVYSLPSNSSIEITFPATTAAPGAPHPFHLHG
HVFAVVRSAGSTSYNYDDPVWRDVVSTGTPQAGDNVTIRFQTDNPGPWFL
HCHIDFHLDAGFAVVMAEDIPNTVNANPVPQAWSNLCPTYDALEPSNE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2qt6 Chain A Residue 512 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2qt6 Crystal structure of a blue laccase from Lentinus tigrinus: evidences for intermediates in the molecular oxygen reductive splitting by multicopper oxidases.
Resolution1.5 Å
Binding residue
(original residue number in PDB)
E341 S367
Binding residue
(residue number reindexed from 1)
E341 S367
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H64 H66 H109 H111 H394 H397 H399 H451 C452 H453 I454 H457 F462
Catalytic site (residue number reindexed from 1) H64 H66 H109 H111 H394 H397 H399 H451 C452 H453 I454 H457 F462
Enzyme Commision number 1.10.3.2: laccase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0052716 hydroquinone:oxygen oxidoreductase activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:2qt6, PDBe:2qt6, PDBj:2qt6
PDBsum2qt6
PubMed17897461
UniProtQ5EBY5

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