Structure of PDB 1k4j Chain A Binding Site BS06

Receptor Information
>1k4j Chain A (length=193) Species: 66271 (Pantoea stewartii subsp. stewartii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMLELFDVSYEELRLGWEVICSQGMESDEFDGPGTRYILGICEGQLVCSV
RFTSLDRPNMITHTFQHCFSDVTLPAYGTESSRFFVDKARARALLGEHYP
ISQVLFLAMVNWAQNNAYGNIYTIVSRAMLKILTRSGWQIKVIKEAFLTE
KERIYLLTLPAGQDDKQQLGGDVVSRTGCPPVAVTTWPLTLPV
Ligand information
Ligand IDREO
InChIInChI=1S/4O.Re/q;;;-1;
InChIKeyWPWXHJFQOFOBAC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[O-][Re](=O)(=O)=O
FormulaO4 Re
NamePERRHENATE
ChEMBL
DrugBank
ZINC
PDB chain1k4j Chain A Residue 406 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1k4j Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		G51 F69 T70 S71 T96 Y135
Binding residue
(residue number reindexed from 1)		G34 F52 T53 S54 T79 Y118
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.184: acyl-homoserine-lactone synthase.
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0061579 N-acyl homoserine lactone synthase activity
Biological Process
GO:0007165 signal transduction
GO:0009372 quorum sensing

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:1k4j, PDBe:1k4j, PDBj:1k4j
PDBsum1k4j
PubMed11931774
UniProtP54656|ESAI_PANSE Acyl-homoserine-lactone synthase (Gene Name=esaI)

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