Structure of PDB 5j3c Chain XY Binding Site BS05

Receptor Information

>5j3c Chain XY (length=260) Species: 331111 (Escherichia coli O139:H28 str. E24377A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRV
EIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRI
HTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRI
THLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRN
LLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQ
EHQADQLAAL

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

5j3c Chain XY Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	5j3c Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Resolution	3.04 Å
Binding residue (original residue number in PDB)	S152 K160
Binding residue (residue number reindexed from 1)	S56 K64
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003747	translation release factor activity
GO:0005515	protein binding
GO:0016149	translation release factor activity, codon specific
GO:0043022	ribosome binding

	Biological Process
GO:0006412	translation
GO:0006415	translational termination

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:5j3c, PDBe:5j3c, PDBj:5j3c
PDBsum	5j3c
PubMed	27681416
UniProt	P0A7I0\|RF1_ECOLI Peptide chain release factor RF1 (Gene Name=prfA)

[Back to BioLiP]