Structure of PDB 4u52 Chain M7 Binding Site BS05

Receptor Information
>4u52 Chain M7 (length=183) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARYGATSTNPAKSASARGSYLRVSFKNTRETAQAINGWELTKAQKYLEQV
LDHQRAIPFRRFNSSIGRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAAN
AEAKGLDATKLYVSHIQVNQAPKQRRRTYRAHGRINKYESSPSHIELVVT
EKEEAVAKAAEKKVVRLTSRQRGRIAAQKRIAA
Ligand information
Ligand IDOHX
InChIInChI=1S/6H2N.Os/h6*1H2;/q6*-1;+6
InChIKeyOWCQTVJQFLTQTE-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01
CACTVS 3.370
OpenEye OEToolkits 1.7.0		N[Os](N)(N)(N)(N)N
FormulaH12 N6 Os
Nameosmium (III) hexammine;
osmium(6+) hexaazanide
ChEMBL
DrugBank
ZINC
PDB chain4u52 Chain M7 Residue 205 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4u52 ?
Resolution3.0 Å
Binding residue
(original residue number in PDB)		D53 Q55
Binding residue
(residue number reindexed from 1)		D52 Q54
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0030687 preribosome, large subunit precursor
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4u52, PDBe:4u52, PDBj:4u52
PDBsum4u52
PubMed25209664
UniProtP05740|RL17A_YEAST Large ribosomal subunit protein uL22A (Gene Name=RPL17A)

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