Structure of PDB 6qdv Chain M Binding Site BS05

Receptor Information
>6qdv Chain M (length=289) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPGVRMRFKK
TEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSFKDDMPKSDVNKEYY
TQNMEREISNSDGTRPVGMLGKATSAAAALLKLARTTPYYKRNRPHICSF
WVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGINDPVADKLLKRA
STMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQ
QCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6qdv Chain M Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6qdv A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		C165 C173 C179 H183
Binding residue
(residue number reindexed from 1)		C148 C156 C162 H166
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6qdv, PDBe:6qdv, PDBj:6qdv
PDBsum6qdv
PubMed30705154
UniProtQ9NW64|RBM22_HUMAN Pre-mRNA-splicing factor RBM22 (Gene Name=RBM22)

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