Structure of PDB 2om7 Chain L Binding Site BS05

Receptor Information
>2om7 Chain L (length=655) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRIAVTTCFWKDHRINIID
TPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRI
AFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRM
KAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLE
GEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSP
LDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSG
TLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKET
ITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAE
EDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAY
RETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGV
IPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFK
IAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILG
MEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQV
QEKLI
Ligand information
>2om7 Chain I (length=58) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gccaggagguuggcuuagaagcagccauccuuuaaagagugcguaauagc
ucacuggu
<<<<..<<...<<<.........>>>...>>.........<........>
....>>>>
Receptor-Ligand Complex Structure
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PDB2om7 Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.
Resolution7.3 Å
Binding residue
(original residue number in PDB)		E614 E615 M617 G618 D619 I631 L632 G633 M634
Binding residue
(residue number reindexed from 1)		E581 E582 M584 G585 D586 I598 L599 G600 M601
Enzymatic activity
Catalytic site (original residue number in PDB) I21
Catalytic site (residue number reindexed from 1) I16
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0032790 ribosome disassembly
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2om7, PDBe:2om7, PDBj:2om7
PDBsum2om7
PubMed17349960
UniProtQ5SHN5|EFG_THET8 Elongation factor G (Gene Name=fusA)

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