Structure of PDB 3glg Chain H Binding Site BS05

Receptor Information

>3glg Chain H (length=365) Species: 83333 (Escherichia coli K-12)

QVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTS
IARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVED
TRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFL
LATADPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRAL
QLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLV
EAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALG
NDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTL
LRALAFHPRMPLPEP

Ligand information

• Ligand ID: BEF
• InChI: InChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
• InChIKey: OGIAHMCCNXDTIE-UHFFFAOYSA-K
• SMILES:
  OpenEye OEToolkits 1.5.0: [Be-](F)(F)F
  ACDLabs 10.04
  CACTVS 3.341: F[Be-](F)F
• Formula: Be F3
• Name: BERYLLIUM TRIFLUORIDE ION
• PDB chain: 3glg Chain I Residue 409

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3glg The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
• Resolution: 3.25 Å
• Binding residue (original residue number in PDB): R47 R215
• Binding residue (residue number reindexed from 1): R44 R212
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.7.7.7: DNA-directed DNA polymerase.

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003887 DNA-directed DNA polymerase activity
• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006260 DNA replication

Cellular Component

• GO:0009360 DNA polymerase III complex

External links

• PDB: RCSB:3glg, PDBe:3glg, PDBj:3glg
• PDBsum: 3glg
• PubMed: 19450514
• UniProt: P06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)