Structure of PDB 7whg Chain G Binding Site BS05

Receptor Information
>7whg Chain G (length=221) Species: 2053489 (Candidatus Lokiarchaeota archaeon) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLFLIVKGELKEIKKNIFSSGDVYLLDADKTIYVWIGNKCSVDEKTTGAA
QARTLDQQRGGAAKIITIDQGFETKDFLKLIAPKIVEKNYAKTLLVDVST
GDWAGFNEWKNILYRASSEEFDGINSMKMVQVGFNKSSLDSEDCFVADLG
NKVYIWQGKSSTVKERVKAGQWARSIDYDRAGLQQETIFEEGDDIEFMAA
LDRGENYKESDAVQLKAESVL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7whg Chain G Residue 405 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7whg Structural and biochemical evidence for the emergence of a calcium-regulated actin cytoskeleton prior to eukaryogenesis
Resolution3.25 Å
Binding residue
(original residue number in PDB)		D57 G62 A63 A64
Binding residue
(residue number reindexed from 1)		D56 G61 A62 A63
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0046872 metal ion binding
GO:0051015 actin filament binding
Biological Process
GO:0051014 actin filament severing
GO:0051016 barbed-end actin filament capping

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7whg, PDBe:7whg, PDBj:7whg
PDBsum7whg
PubMed
UniProtA0A0F8Y9R4

[Back to BioLiP]