Structure of PDB 7od0 Chain FFF Binding Site BS05

Receptor Information
>7od0 Chain FFF (length=268) Species: 28112 (Tannerella forsythia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSSTILIPVVVHVVYNNSAQNISDAQIISQIQVLNEDFRRMNADQANTPS
AFANLAGNANIEFKLARRDPNGNTTNGITRTSTSTETFSMEMDNVKFSNL
GGNNAWNTRRYLNIWVCNLGLLGYAQFPFEFQTKPNTDGVVIHYKHFGRD
GSAESPYDKGRTATHEVGHWLDLRHIWGDDGGSCSGTDNIADTPNQGGYN
EGCPSFPKTDHCTNTSPGVMFMNYMDYTYDACMNLFTKGQVERMRSLFDT
QTGIRREMQIYANELTNP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7od0 Chain FFF Residue 408 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7od0 Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia .
Resolution2.1 Å
Binding residue
(original residue number in PDB)		H205 Y216 G219 R220 T221 D289
Binding residue
(residue number reindexed from 1)		H146 Y157 G160 R161 T162 D230
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:7od0, PDBe:7od0, PDBj:7od0
PDBsum7od0
PubMed34210221
UniProtA0A0F7IPS1

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