Structure of PDB 7b2h Chain E Binding Site BS05

Receptor Information
>7b2h Chain E (length=441) Species: 79929 (Methanothermobacter marburgensis str. Marburg) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEG
IENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTN
VELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYD
ANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVA
ATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLV
FDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMW
NAYAAAGLMAATMVNQGAARAAQGVSSTLLYYNDLIEFETGLPSVDFGKV
EGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDAG
TQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI
Ligand information
Ligand IDXE
InChIInChI=1S/Xe
InChIKeyFHNFHKCVQCLJFQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Xe]
FormulaXe
NameXENON
ChEMBLCHEMBL1236802
DrugBankDB13453
ZINC
PDB chain7b2h Chain E Residue 508 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7b2h Crystal structure of a key enzyme for anaerobic ethane activation.
Resolution2.12 Å
Binding residue
(original residue number in PDB)		A47 F419
Binding residue
(residue number reindexed from 1)		A45 F417
Annotation score1
Enzymatic activity
Enzyme Commision number 2.8.4.1: coenzyme-B sulfoethylthiotransferase.
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0050524 coenzyme-B sulfoethylthiotransferase activity
Biological Process
GO:0015948 methanogenesis
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7b2h, PDBe:7b2h, PDBj:7b2h
PDBsum7b2h
PubMed34210888
UniProtP11560|MCRB_METTM Methyl-coenzyme M reductase I subunit beta (Gene Name=mcrB)

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