Structure of PDB 8j5t Chain D Binding Site BS05

Receptor Information
>8j5t Chain D (length=608) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPLLEVTDLAVTFRTDGDPVTAVRGISYRVEPGEVVAMVGESGSGKSAAA
MAVVGLLPEYAQVRGSVRLQGTELLGLADNAMSRFRGKAIGTVFQDPMSA
LTPVYTVGDQIAEAIEVHQPRVGKKAARRRAVELLDLVGISQPQRRSRAF
PHELSGGERQRVVIAIAIANDPDLLICDDPTTALDVTVQAQILDVLKAAR
DVTGAGVLIITHDLGVVAEFADRALVMYAGRVVESAGVNDLYRDRRMPYT
VGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLAPGCPFAPRCPLVIDECLT
AEPELLDVATDHRAACIRTELVTGRSAADIYRVKTEARPAALGDASVVVR
VRHLVKTYRLAKGVVLRRAIGEVRAVDGISLELRQGRTLGIVGESGSGKS
TTLHEILELAAPQSGSIEVLGTDVATLGTAERRSLRRDIQVVFQDPVASL
DPRLPVFDLIAEPLQANGFGKNETHARVAELLDIVGLRHGDASRYPAEFS
GGQKQRIGIARALALQPKILALDDPVSALDVSIQAGIINLLLDLQEQFGL
SYLFVSHDLSVVKHLAHQVAVMLAGTVVEQGDSEEVFGNPKHEYTRRLLG
AVPQPDPA
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8j5t Chain D Residue 705 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8j5t An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality
Resolution2.98 Å
Binding residue
(original residue number in PDB)		P249 C286 A289 C292 C299 C317 R319
Binding residue
(residue number reindexed from 1)		P248 C285 A288 C291 C298 C316 R318
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0015833 peptide transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8j5t, PDBe:8j5t, PDBj:8j5t
PDBsum8j5t
PubMed38548954
UniProtP9WQJ5|Y1281_MYCTU Uncharacterized ABC transporter ATP-binding protein Rv1281c (Gene Name=Rv1281c)

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