Structure of PDB 5yhw Chain D Binding Site BS05

Receptor Information

>5yhw Chain D (length=387) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TVKVINDPIHGHIELHPLLIRIIDTPQFQRLRYIKQLGGGYYVFPGASHN
RFEHSLGVGYLAGCLVRELSEKQPELQISERDMLCVQIAGLCRNLGHGPF
SHMFDGRFIPLARPDVKWTHEQGSVNMFEHLVNSNGLIDVMEHYGLIPEE
DIWFIKEQITWPYKGRPKEKSFLYEIVANKRNGIDVDKWDYFARDCHHLG
IQNNFDYKRFIKFARVCEVDNKKHICTREKEVGNLYDMFHTRNCLHRRAY
QHKVGNIIDTMITDAFLKADPYIEITGKKYRISTAIDDMEAFTKLTDNIF
LEILYSTDPKLDAARAILKKIECRNLYKFVIVDVINMDYGMEDKNPIDNV
RFYCKSDPNKAIIITKNQVSQLLPERFAEQLIRVYCK

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

5yhw Chain D Residue 704 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5yhw Structural characterization and directed modification of Sus scrofa SAMHD1 reveal the mechanism underlying deoxynucleotide regulation.
Resolution	2.7 Å
Binding residue (original residue number in PDB)	R206 D309
Binding residue (residue number reindexed from 1)	R93 D185
Annotation score	1

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:5yhw, PDBe:5yhw, PDBj:5yhw
PDBsum	5yhw
PubMed	31152619
UniProt	I3LG77

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