Structure of PDB 3om3 Chain D Binding Site BS05

Receptor Information

>3om3 Chain D (length=256) Species: 272943 (Cereibacter sphaeroides 2.4.1)

LEIIGRPQPGGTGFQPSASPVATQIHWLDGFILVIIAAITIFVTLLILYA
VWRFHEKRNKVPARFTHNSPLEIAWTIVPIVILVAIGAFSLPVLFNQQEI
PEADVTVKVTGYQWYWGYEYPDEEISFESYMIGSPATGGDNRMSPEVEQQ
LIEAGYSRDEFLLATDTAMVVPVNKTVVVQVTGADVIHSWTVPAFGVKQD
AVPGRLAQLWFRAEREGIFFGQCSELCGISHAYMPITVKVVSEEAYAAWL
EQHHHH

Ligand information

• Ligand ID: CU1
• InChI: InChI=1S/Cu/q+1
• InChIKey: VMQMZMRVKUZKQL-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [Cu+]
• Formula: Cu
• Name: COPPER (I) ION
• PDB chain: 3om3 Chain D Residue 286

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3om3 Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
• Resolution: 2.6 Å
• Binding residue (original residue number in PDB): H217 C252 C256 M263
• Binding residue (residue number reindexed from 1): H188 C223 C227 M234
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 7.1.1.9: cytochrome-c oxidase.

Gene Ontology

Molecular Function

• GO:0004129 cytochrome-c oxidase activity
• GO:0005507 copper ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0022900 electron transport chain
• GO:0042773 ATP synthesis coupled electron transport
• GO:1902600 proton transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:3om3, PDBe:3om3, PDBj:3om3
• PDBsum: 3om3
• PubMed: 21205904
• UniProt: Q3J5G0