Structure of PDB 7whf Chain C Binding Site BS05

Receptor Information

>7whf Chain C (length=225) Species: 1841598 (Candidatus Heimdallarchaeota archaeon LC_3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MVKVLHVQGKKLKEVQSPYNFLNGDVYVIDDSKKPDGSDKDPVDSPKVYI
WLGSKAYADDRGVGAWAAKMLDKENQAIDIDTEVEGKESAEFKTIVDFSV
VEGDTPGFLKHVEVNFQDVDYEMYRVYDTDLSDGSSSDDIEIDPVPLSKN
SLKSEDVFVIDGWNDIYVWIGSKSQVGEKAAGNRLARKLDTERKRTPMVY
TVNEGLEPNGFFEFLEKLEQEDPKK

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

7whf Chain C Residue 305 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7whf Structural and biochemical evidence for the emergence of a calcium-regulated actin cytoskeleton prior to eukaryogenesis
Resolution	2.1 Å
Binding residue (original residue number in PDB)	D128 D130 D133 S135 D138 D139
Binding residue (residue number reindexed from 1)	D128 D130 D133 S135 D138 D139
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0046872	metal ion binding
GO:0051015	actin filament binding

	Biological Process
GO:0051014	actin filament severing
GO:0051016	barbed-end actin filament capping

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Molecular Function

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Biological Process

External links

PDB	RCSB:7whf, PDBe:7whf, PDBj:7whf
PDBsum	7whf
PubMed
UniProt	A0A1Q9NVH4

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