Structure of PDB 6cik Chain C Binding Site BS05

Receptor Information
>6cik Chain C (length=602) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEH
RQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQ
IFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSV
DEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVV
KESCDGMGDVSEKVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELC
CKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFI
FRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHA
ENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNA
AEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNG
NFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKE
CPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDG
SIGAWNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNA
HN
Ligand information
Receptor-Ligand Complex Structure
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PDB6cik Cracking the DNA Code for V(D)J Recombination.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		R440 N443 H445 N850 N852 K966
Binding residue
(residue number reindexed from 1)		R45 N48 H50 N449 N451 K561
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cik, PDBe:6cik, PDBj:6cik
PDBsum6cik
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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