Structure of PDB 6cij Chain C Binding Site BS05

Receptor Information
>6cij Chain C (length=616) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRA
RNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAI
TGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGL
ASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPF
TVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVF
EEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEM
GGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNL
VFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSI
DALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRM
NLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKP
VWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLA
HVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHH
WLYTSKYLQKFMNAHN
Ligand information
>6cij Chain M (length=41) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cacagtgatgcaaatcaagtgtgaagccagacaaaaacccg
Receptor-Ligand Complex Structure
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PDB6cij Cracking the DNA Code for V(D)J Recombination.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		R440 S648 N852 R855 R894 S896 E901
Binding residue
(residue number reindexed from 1)		R49 S257 N461 R464 R503 S505 E510
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cij, PDBe:6cij, PDBj:6cij
PDBsum6cij
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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