Structure of PDB 4gx1 Chain C Binding Site BS05

Receptor Information
>4gx1 Chain C (length=546) Species: 243231 (Geobacter sulfurreducens PCA) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLKVLLLYCAFLLVMLLAYASIFRYLMWHLEGRAYSFMAGIYWTITVMTT
LGFGDITFESDAGYLFASIVTVSGVIFLDIILPFGFVSMFLAPWIERRLR
YHPTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVTDNYDQALH
LEEQEGFKVVYGSPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRSL
CQTPIIAVVKEPVHGELLRLAGANQVVPLTRILGRYLGIRATTCGALAHI
LDSFGNLQIAELPVHGTPFAGKTIGESGIRQRTGLSIIGVWERGSLTTPQ
RETVLTEQSLLVLAGTKSQLAALEYLIGEAPEDELIFIIGHGRIGCAAAA
FLDRKPVPFILIDRQESPVCNDHVVVYGDATVGQTLRQAGIDRASGIIVT
TNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASV
GANILGNLLEHKESAFLSEGMAVFRRPLPPAMAGKTIAETRLRPLTGCSI
VAIEAPDRADILISPPPETILAEGARLILIGTSEQEKTFDQTIAAR
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain4gx1 Chain C Residue 609 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4gx1 Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		P376 F377
Binding residue
(residue number reindexed from 1)		P358 F359
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003674 molecular_function
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0006813 potassium ion transport
GO:0008150 biological_process
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4gx1, PDBe:4gx1, PDBj:4gx1
PDBsum4gx1
PubMed23240087
UniProtQ74FS9

[Back to BioLiP]