Structure of PDB 3tbc Chain C Binding Site BS05

Receptor Information
>3tbc Chain C (length=277) Species: 67581 (Streptomyces viridosporus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PAKTAPAGGEVKRIKLYAERLGGGQMGYGLEKGKATIPGPLIELNEGDTL
HIEFENTMDVPVSLHVHGLDYEISSDGTKQSRSDVEPGGTRTYTWRTHVP
GRRADGTWRAGSAGYWHYHDHVVGTEHGTGGIRNGLYGPVIVRRKGDVLP
DRTHTIVFNDMTINNRPAHTGPDFEATVGDRVEFVMITHGEYYHTFHLHG
HRWADNRTGMLTGPDDPSQVIDNKICGPADSFGFQVIAGEGVGAGAWMYH
CHVQSHSDMGMVGLFLVKKPDGTIPGY
Ligand information
Ligand IDI75
InChIInChI=1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3
InChIKeyDFYRUELUNQRZTB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.2CC(=O)c1ccc(c(c1)OC)O
ACDLabs 12.01O=C(c1cc(OC)c(O)cc1)C
CACTVS 3.370COc1cc(ccc1O)C(C)=O
FormulaC9 H10 O3
Name1-(4-hydroxy-3-methoxyphenyl)ethanone
ChEMBLCHEMBL346919
DrugBankDB12618
ZINCZINC000000162515
PDB chain3tbc Chain C Residue 349 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3tbc Roles of small laccases from Streptomyces in lignin degradation.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		M193 T194
Binding residue
(residue number reindexed from 1)		M161 T162
Annotation score1
Enzymatic activity
Enzyme Commision number 1.10.3.2: laccase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0052716 hydroquinone:oxygen oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:3tbc, PDBe:3tbc, PDBj:3tbc
PDBsum3tbc
PubMed24870309
UniProtJ9PBR2

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