Structure of PDB 3t6w Chain C Binding Site BS05

Receptor Information
>3t6w Chain C (length=495) Species: 92696 (Steccherinum ochraceum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VQIGPVTDLHIVNADIVPDGFVRPAVNAGGTFPGPVIAGNVGDNFQIVTF
NQLIECSMLVDTSIHWHGEFQKGTNWADGPAFITQCPIIVGNSFSYNFNV
PGMAGTYWYHSHLTTQYCDGLRGPFVVYDPNDPDANLYDVDDDTTIITLA
DWYHVLAKEMGAGGAITADSTLIDGLGRTHVNVAAVPLSVITVEVGKRYR
MRLVSISCDPNYDFSIDGHDMTIIETDGVDSQELTVDEIQIFAAQRYSFV
LNANQPVGNYWIRANPNSGGEGFDGGINSAILRYDGATTADPVTVASTVH
TKCLIETDLHPLSRNGVPGNPHQGGADCNLNLSLGFACGNFVINGVSFTP
PTVPVLLQICSGANTAADLLPSGSVISLPSNSTIEIALPAGAAGGPHPFH
LHGHDFAVSESASNSTSNYDDPIWRDVVSIGGVGDNVTIRFCTDNPGPWF
LHCHIDWHLDAGFAIVFAEDIPNTASANPVPEAWSNLCPSYDSAH
Ligand information
Ligand IDOXY
InChIInChI=1S/O2/c1-2
InChIKeyMYMOFIZGZYHOMD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		O=O
FormulaO2
NameOXYGEN MOLECULE
ChEMBLCHEMBL1234886
DrugBankDB09140
ZINC
PDB chain3t6w Chain C Residue 511 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3t6w Reaction intermediates and redox state changes in a blue laccase from Steccherinum ochraceum observed by crystallographic high/low X-ray dose experiments.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		H65 H110 H112 H400 H402 H452 H454
Binding residue
(residue number reindexed from 1)		H65 H110 H112 H400 H402 H452 H454
Annotation score5
Enzymatic activity
Catalytic site (original residue number in PDB) H65 H67 H110 H112 H397 H400 H402 H452 C453 H454 I455 H458 F463
Catalytic site (residue number reindexed from 1) H65 H67 H110 H112 H397 H400 H402 H452 C453 H454 I455 H458 F463
Enzyme Commision number 1.10.3.2: laccase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0052716 hydroquinone:oxygen oxidoreductase activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3t6w, PDBe:3t6w, PDBj:3t6w
PDBsum3t6w
PubMed22341982
UniProtI1SB14

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