Structure of PDB 2uzp Chain C Binding Site BS05

Receptor Information
>2uzp Chain C (length=142) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMHTERRGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLI
PDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTS
RNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2uzp Chain C Residue 1298 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2uzp Crystal Structure of C2 Domain of Protein Kinase C Gamma
Resolution2.0 Å
Binding residue
(original residue number in PDB)		M186 D187 D246 D248 D254
Binding residue
(residue number reindexed from 1)		M35 D36 D95 D97 D103
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.13: protein kinase C.
External links
PDB RCSB:2uzp, PDBe:2uzp, PDBj:2uzp
PDBsum2uzp
PubMed
UniProtP05129|KPCG_HUMAN Protein kinase C gamma type (Gene Name=PRKCG)

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