Structure of PDB 1sl6 Chain C Binding Site BS05

Receptor Information
>1sl6 Chain C (length=168) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEKSKLQEIYQELTQLKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNC
YFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMG
LSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSGWNDN
RCDVDNYWICKKPAACFR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1sl6 Chain C Residue 4 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1sl6 Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Resolution2.25 Å
Binding residue
(original residue number in PDB)		E253 D256
Binding residue
(residue number reindexed from 1)		E24 D27
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1sl6, PDBe:1sl6, PDBj:1sl6
PDBsum1sl6
PubMed15195147
UniProtQ9H2X3|CLC4M_HUMAN C-type lectin domain family 4 member M (Gene Name=CLEC4M)

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