Structure of PDB 8ove Chain BT Binding Site BS05

Receptor Information
>8ove Chain BT (length=192) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLKLQARLAADILRCGRGRVWLDPNEAVEIRNANSRKSVRKLIKDGLVMR
KPVKVHSRSRWRQMKLAKSMGRHEGTGRREGTREARMPSKDLWMRRLRIL
RRLLRKYREEKKIDRHIYRELYMKAKGNVFRNKRNLMEHIHKVKNEKKKA
RQLAEQLAAKRLKDEQNRRKARKQELKKREKERERARRDDAA
Ligand information
>8ove Chain BG (length=183) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gugagauugugaagggaucucgcaggcaucgugagggaaguaugggguag
uacgagaggaacucccaugccgugccucugguuucuggaguuugucgaag
ggcaagugcuccgacgcuaucgcacggugguucucggcugaacgccucua
agccagaaaccagucccaagaccgggugcccgu
<<<<<<<.........>>>>>>>.<<<<<<....<<<<.<<<<<<<<...
............>>>>>>>><<<<<...<<<<....<<<<<<<<<.....
.>>>>..>>>>>...>>>>..>>>>>.<<<<..<.<<<<...........
>>>>.>..>>>>.>>>>.......>>>>>>...
Receptor-Ligand Complex Structure
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PDB8ove A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		H58 S59 S61 R62 R80
Binding residue
(residue number reindexed from 1)		H56 S57 S59 R60 R78
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ove, PDBe:8ove, PDBj:8ove
PDBsum8ove
PubMed37985661
UniProtQ57ZI7

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