Structure of PDB 8ove Chain BR Binding Site BS05

Receptor Information
>8ove Chain BR (length=150) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YSRKPQVSSKTAKAKIADLRCHYKNTFETANVINGMKLRKAQQLYRQVLA
KTRCIPFKRYNGKIGNTAQAKEWGQTKGRWPRKSVVAMLSLLKNAEANAI
EKGLDPGKMVIKHVQVDQAPRVRRRTFRAHGRITPYMRSPCHVQLFMTQP
Ligand information
>8ove Chain BH (length=118) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugucccucuccaaacgagaguacaugcaugggcuggcaugagcggcacgc
uccauggggcucgaggggcaccgucccgaggcgcugaaccuugaugcuug
gaaucaugcucagggacu
.<<<<<.<<<.......>>>.....<<<<<<<<.<<.....<<<....<.
<<<...>>>.>....<<<......>>>....>>>....>>.....>>>..
....>>>>>...>>>>>.
Receptor-Ligand Complex Structure
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PDB8ove A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		N69 K74
Binding residue
(residue number reindexed from 1)		N66 K71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ove, PDBe:8ove, PDBj:8ove
PDBsum8ove
PubMed37985661
UniProtQ385T6

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